Genetics of Lipodystrophy

Pneumoviruses: Molecular Genetics and Reverse Genetics

Pneumoviruses are responsible for significant respiratory disease in their hosts and represent a major problemfor human and animal health. Pneumoviruses are members of the family Paramyxoviridae, subfamilyPneumovirinae and the virus particles consist of a negative-sense, nonsegmented RNA genome within a helical nucleocapsid structure enveloped in a lipid membrane derived from the ho...

Generalized Lipodystrophy.

Novel Forms of Lipodystrophy

L ipodystrophies are a heterogeneous group of conditions in which individuals never develop or progressively lose adipose tissue in parts or all of their bodies (1,2) (Table 1). In this commentary, we will make the case that 1) defining lipodystrophy is a work in progress; 2) not all forms of lipodystrophy are very rare; 3) lipodystrophy and obesity can occur simultaneously and their metabolic ...

[Mesenteric lipodystrophy].

Mesenteric lipodystrophy is a rare disorder characterized by either focal or diffuse thickening of the mesentery due to chronic inflammation and fibrosis. The etiology and pathogenesis is obscure. Roentgenologic findings help in differential diagnosis with other diseases but they rarely establish the diagnosis. This is made in most cases by laparotomy.

Molecular Genetics and Epidemiology of Vitiligo

Background: Vitiligo is an acquired, idiopathic, and common depigmentation disorder of the skin that affects people of all ages and both sexes equally in the worldwide. Although etiology of the disease is unknown, there are theories such as environment and genetic factors. Methods: In this article, we collected and summarized the appropriate manuscripts regarding the epidemiology and gene...